Vitiligo is a condition that causes loss of pigment in the skin, resulting in white spots and patches. It occurs when melanocytes (pigment cells in the skin) are destroyed and can no longer produce melanin. Persons with vitiligo may have associated autoimmune diseases such as diabetes mellitus and thyroid disease. Therapeutic modalities include topical medication, phototherapy, laser therapy and surgical grafting. The response to treatment is however variable, and differs from person to person and site of involvement.